About Pfam

Pfam version 35.0 was produced at the European Bioinformatics Institute using a sequence database called Pfamseq, which is based on UniProt release 2021_03.

Pfam is freely available under the Creative Commons Zero (“CC0”) licence.

Pfam is powered by the HMMER3 package written by Sean Eddy and his group at HHMI/ Harvard University, and built by the Xfam consortium.

Pfam is supported by the following organisations:

EMBL is EMBL-EBI’s parent organisation. It provides core funding (staff, space, equipment) for Pfam.

The Wellcome Trust has supported Pfam since the database inception, via core funding when based at the Wellcome Trust Sanger Institute. As well as providing and maintaining the campus on which the EMBL-EBI is located, the Wellcome Trust also now provides significant funding for Pfam (grant 221320/Z/20/Z). The current grant runs from October 2020 to September 2025.

BBSRC is supporting Pfam activities (BB/S020381/1) from November 2019 to October 2023 and has previously supported Pfam activities via grants BB/L024136/1 and BB/N00521X/1.

The Howard Hughes Medical Institute supports the Eddy group.

Many organisations have supported Pfam activities in the past.

For more information, please contact the Pfam helpdesk.