Welcome to Pfam’s documentation

Pfam is a large collection of protein families, each represented by multiple sequence aligments and profile hidden Markov models (HMMs).


Pfam is freely available under the Creative Commons Zero (“CC0”) licence.

Citing Pfam

If you use Pfam in your work, please consider citing the Pfam References.

Get in touch

If you have any questions or feedback, email us at pfam-help@ebi.ac.uk.